KinATLAS
TranscriptoNET
PhosphoNET
OncoNET
KinaseNET
DrugKiNET
KiNET-AM
Kinetica Online
Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
|
Home
|
Kinexus
|
Contact
|
Credits
Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
PLCH2
All Species:
21.52
Human Site:
S776
Identified Species:
47.33
UniProt:
O75038
Number Species:
10
Phosphosite Substitution
Charge Score:
0.1
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
O75038
NP_055453.2
1416
154668
S776
Q
L
P
K
P
R
D
S
M
L
G
D
R
G
E
Chimpanzee
Pan troglodytes
XP_001149239
1685
188441
S762
Q
L
P
K
P
P
D
S
M
F
G
D
R
G
E
Rhesus Macaque
Macaca mulatta
XP_001085424
1423
155915
S783
Q
L
P
K
P
R
D
S
M
L
G
D
R
G
E
Dog
Lupus familis
XP_546733
1387
151432
S760
Q
L
P
K
P
R
D
S
M
L
G
D
R
G
E
Cat
Felis silvestris
Mouse
Mus musculus
A2AP18
1501
164279
S857
Q
L
P
K
P
R
D
S
V
L
G
D
R
G
E
Rat
Rattus norvegicus
Q62688
1096
122754
K533
S
Y
L
P
S
P
E
K
L
K
H
M
I
I
V
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
Chicken
Gallus gallus
Q2VRL0
637
72514
E74
R
A
I
V
H
R
N
E
F
H
E
I
F
C
A
Frog
Xenopus laevis
Q32NH8
758
87399
F195
G
T
L
E
G
E
E
F
V
L
F
Y
K
A
L
Zebra Danio
Brachydanio rerio
A5D6R3
784
89362
E221
R
L
D
H
V
E
I
E
E
F
C
R
E
M
M
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
P25455
1318
146373
N753
F
L
T
D
K
R
A
N
T
F
V
E
V
D
M
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
XP_783611
2724
302530
S851
Q
L
P
K
P
P
Q
S
L
L
G
E
R
G
E
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
46.4
94
78.7
N.A.
77.2
21.2
N.A.
N.A.
21.2
24.7
24.5
N.A.
24.2
N.A.
N.A.
26.4
Protein Similarity:
100
59.9
95.4
82.9
N.A.
81.6
36.7
N.A.
N.A.
30.7
35.3
35
N.A.
40.3
N.A.
N.A.
35.7
P-Site Identity:
100
86.6
100
100
N.A.
93.3
0
N.A.
N.A.
6.6
6.6
6.6
N.A.
13.3
N.A.
N.A.
73.3
P-Site Similarity:
100
86.6
100
100
N.A.
100
13.3
N.A.
N.A.
20
33.3
13.3
N.A.
26.6
N.A.
N.A.
86.6
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
10
0
0
0
0
10
0
0
0
0
0
0
10
10
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
10
0
0
10
0
% C
% Asp:
0
0
10
10
0
0
46
0
0
0
0
46
0
10
0
% D
% Glu:
0
0
0
10
0
19
19
19
10
0
10
19
10
0
55
% E
% Phe:
10
0
0
0
0
0
0
10
10
28
10
0
10
0
0
% F
% Gly:
10
0
0
0
10
0
0
0
0
0
55
0
0
55
0
% G
% His:
0
0
0
10
10
0
0
0
0
10
10
0
0
0
0
% H
% Ile:
0
0
10
0
0
0
10
0
0
0
0
10
10
10
0
% I
% Lys:
0
0
0
55
10
0
0
10
0
10
0
0
10
0
0
% K
% Leu:
0
73
19
0
0
0
0
0
19
55
0
0
0
0
10
% L
% Met:
0
0
0
0
0
0
0
0
37
0
0
10
0
10
19
% M
% Asn:
0
0
0
0
0
0
10
10
0
0
0
0
0
0
0
% N
% Pro:
0
0
55
10
55
28
0
0
0
0
0
0
0
0
0
% P
% Gln:
55
0
0
0
0
0
10
0
0
0
0
0
0
0
0
% Q
% Arg:
19
0
0
0
0
55
0
0
0
0
0
10
55
0
0
% R
% Ser:
10
0
0
0
10
0
0
55
0
0
0
0
0
0
0
% S
% Thr:
0
10
10
0
0
0
0
0
10
0
0
0
0
0
0
% T
% Val:
0
0
0
10
10
0
0
0
19
0
10
0
10
0
10
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
10
0
0
0
0
0
0
0
0
0
10
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _